Botox® onabotulinumtoxinA On our shelf | Allergan Aesthetics (AbbVie) | 2002 — first cosmetic approval in the U.S. | ~3–5 days, full effect ~2 weeks | ~3–4 months | The original and the benchmark — the largest body of clinical data and the widest range of approved cosmetic and therapeutic uses.The gold standard for frown lines, forehead lines and crow’s feet. |
Dysport® abobotulinumtoxinA On our shelf | Ipsen / Galderma | 2009 | Fast — often ~2–3 days | ~3–4 months | Wider natural spread and its own unit scale (not interchangeable with Botox units — a conversion your injector handles).Broad, even softening across larger zones like the forehead; quick onset. |
Xeomin® incobotulinumtoxinA On our shelf | Merz Aesthetics | 2011 | ~3–6 days, full effect 1–2 weeks | ~3–4 months | “Naked” toxin — purified to remove complexing proteins, which may matter for guests who have developed resistance to other brands.Purity-first guests and toxin switchers whose results have faded early. |
Letybo® letibotulinumtoxinA-wlbg On our shelf | Hugel | 2024 — the newest U.S. cosmetic approval | ~2–3 days, full effect ~1–2 weeks | ~3–4 months | The most-used aesthetic toxin brand in South Korea for years before its U.S. arrival — a K-beauty staple with a long international track record.Guests who want the newest option on the U.S. market, proven abroad first. |
Jeuveau® prabotulinumtoxinA By requestOn our shelf: Botox — the benchmark Jeuveau was modeled on, with a two-decade record. | Evolus | 2019 | ~2–3 days, peak ~2 weeks | ~3–4 months | “Newtox” — a modern formulation similar to Botox, developed exclusively for aesthetics (no therapeutic indications).A dedicated cosmetic-only alternative for frown lines. |
Daxxify® daxibotulinumtoxinA By requestOn our shelf: Botox or Dysport on a planned cadence — we time touch-ups so the wear never shows, without switching to the newest formula. | Revance Therapeutics | 2022 | Fast — often ~1–2 days | Longest — median ~6 months, up to ~9 in some guests | First peptide-stabilized neuromodulator — no human or animal-derived stabilizers.Guests who want the fewest touch-up visits per year. |
